Article
Isolation of Disease-relevant p53 for Cryo-Electron Microscopy Analysis
2021-01-21
Abstract excerpt
<title>Abstract</title> <p>Tumor suppressor protein TP53 (p53) plays a multi-faceted role in all cells of thehuman body. Sadly, mutations in the TP53 gene are involved in nearly ~50% of tumors,spurring erratic cell growth and disease progression. Until recently, structural informationfor p53 remained incomplete and there are limited studies on native p53 produced inhuman tumors. Here, we present a highly reproduc...
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Identifiers and source
- Literature Corpus work
- 290c7ed3-9f38-5136-867d-87c6728c0e1d
- DOI
- 10.21203/rs.3.pex-1294/v1