Article

The silencing of the L1-MET chimeric transcript activates cancer cell death program and inhibits the expression of crucial oncoproteins in lung cancer cells

2023-08-25

Abstract excerpt

<title>Abstract</title> Background Among the antisense chimeric sequences generated by intragenic long interspersed nuclear elements (LINE1s), L1-<italic>MET</italic> transcript, within <italic>MET</italic> oncogene, is of particular interest since its expression, activated by promoter hypomethylation, has been associated with the acquisition of cancer phenotype. L1-<italic>MET</italic> can originate several...

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Literature Corpus work: 28ca6f93-2da1-5347-993b-df4ed9edb922
DOI: 10.21203/rs.3.rs-3249117/v1

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