Article
The evolutionary consequences of alternative types of imperfect vaccines.
Journal of mathematical biology - 1 Mar 2014
Magori Krisztian, Park Andrew W
Abstract excerpt
The emergence and spread of mutant pathogens that evade the effects of prophylactic interventions, including vaccines, threatens our ability to control infectious diseases globally. Imperfect vaccines (e.g. those used against influenza), while not providing life-long immunity, confer protection by reducing a range of pathogen life-history characteristics; conversely, mutant pathogens can gain an advantage by...
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