Article

Wnt6 Plays a Complex Role in Maintaining Human Limbal Stem/Progenitor Cells

2021-07-12

Abstract excerpt

The cornea is consistently regenerated by limbal stem/progenitor cells (LSCs), a very small population of adult stem cells residing in the limbus. Several Wnt ligands, including Wnt6, are preferentially expressed in the limbus. To investigate the role of Wnt6 in regulating proliferation and maintenance of human LSCs in an in vitro LSC expansion setting, we generated NIH-3T3 feeder cells to overexpress different le...

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Literature Corpus work: 2861f1a6-26b4-54d5-9003-5f9e37b4c07a
DOI: 10.21203/rs.3.rs-679836/v1

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