Article

Human and mouse iPSC-derived astrocyte subtypes reveal vulnerability in Vanishing White Matter

2019-01-17

Abstract excerpt

Astrocytes gained attention as important players in neurological disease, including a number of leukodystrophies. Several studies explored the generation of induced pluripotent stem cell-derived astrocytes for drug screening and regenerative studies. Developing robust models of patient induced pluripotent stem cells is challenged by high variability due to diverse genetic backgrounds and long-term culture procedur...

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Literature Corpus work: 2836682b-7af3-5a05-ab01-b247ca0f243e
DOI: 10.1101/523233

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