Article

Txnip deletions and missense alleles prolong the survival of cones in a retinitis pigmentosa mouse model

2023-08-05

Abstract excerpt

Retinitis pigmentosa (RP) is a prevalent inherited retinal degenerative disease worldwide, affecting 1 in 4,000 people. The disease is characterized by an initial loss of night vision followed by a loss of daylight and color vision. Many of the RP disease genes are expressed in the rod photoreceptors, the cell type that initiates dim light vision. Following loss of rods, the cone photoreceptors, which initiate day...

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Literature Corpus work: 28114441-4c90-52a3-a94d-b6ecd15349f6
DOI: 10.1101/2023.08.03.551766

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