Article

A novel subclonal rearrangement of the STRN3::PDGFRB genes in de novo acute myeloid leukemia with NPM1 mutation and its leukemogenic effects

2023-03-23

Abstract excerpt

<title>Abstract</title> Chromosome translocations in the 5q31-33 region are associated with a range of hematologic malignancies, some of which involve the platelet derived growth factor receptor beta (<italic>PDGFRB</italic>) gene. We report a case of acute myeloid leukemia (AML) with a mutation in the <italic>NPM1</italic> gene (<italic>NPM1</italic>-mut AML) and a subclonal gene rearrangement involving the <...

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Literature Corpus work: 27d317b4-7beb-5480-bd67-189671e178fc
DOI: 10.21203/rs.3.rs-2716740/v1

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A novel subclonal rearrangement of the STRN3::PDGFRB genes in de novo acute myeloid leukemia with NPM1 mutation and its leukemogenic effectsDOI 10.21203/rs.3.rs-2716740/v1Read

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