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Article

3q26/EVI1 rearrangement in myelodysplastic/myeloproliferative neoplasms: An early event associated with a poor prognosis.

Leukemia research - 1 Feb 2018

Hu Zhihong, Hu Shimin, Ji Changsheng, Tang Zhenya, Thakral Beenu, Loghavi Sanam, Medeiros L Jeffrey, Wang Wei

Abstract excerpt

3q26.2/EVI1 rearrangements resulting in EVI1 overexpression play an important role in leukemogenesis and are associated with treatment resistance and a poorer prognosis in patients with acute myeloid leukemia, myelodysplastic syndrome, chronic myeloid leukemia and BCR-ABL negative myeloproliferative neoplasms. In this study, we aim to explore the clinicopathological features of myelodysplastic/myeloproliferative...

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Source

Identifiers

PMID: 29288910
DOI: 10.1016/j.leukres.2017.12.004

Genes

ASXL1
BCR
FLT3
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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3q26/EVI1 rearrangement in myelodysplastic/myeloproliferative neoplasms: An early event associated with a poor prognosis.PMID 29288910Read ↗

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