Article

Population structure in the MHC region

2021-10-26

Abstract excerpt

In his 1972 “The apportionment of human diversity”, Lewontin showed that, when averaged over loci, genetic diversity is predominantly attributable to differences among individuals within populations. However, selection on specific genes and genomic regions can alter the apportionment of diversity. We examine genetic diversity at the HLA loci, located within the MHC region. HLA genes code for proteins that are crit...

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Literature Corpus work: 27cc468b-484a-5aad-847a-f27156a61ca1
DOI: 10.1101/2021.10.25.465726

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