Article

Glycine nitrosation and signature mutations in the p53 tumour suppressor gene : a molecular link between diet and cancers of the gastro-intestinal tract

2007-01-01

Abstract excerpt

Genotoxic agents derived from diet may contribute to the total human burden of potentially carcinogenic DNA damage. For example, glycine is a simple primary amino acid and a commonly found dietary constituent in the red meat. The nitrosation of glycine would probably constitute a major source of alkylating agents, as glycine is one of the most abundant amino acids found in nature. It has been shown that <i>O</i><s...

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Literature Corpus work: 27c4f579-215b-5b1c-9520-3dd4ad4b347c
DOI: 10.21954/ou.ro.0000fb24

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