OAS Gene Family Expression is Associated with Clinical Outcomes in Human Cancers

Abstract excerpt

The 2’, 5’-oligoadenylate synthetase (OAS) gene family plays an active role in antiviral immunity. Given their role in apoptosis and autoimmunity, aberrant expression of the OAS genes has been implicated in carcinogenesis. However, there has been minimal investigation of their potential role in tumorigenesis. Therefore, in this study, we used data from publicly available databases to examine the expression pattern...

Topics

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• 2',5'-Oligoadenylate Synthetase
• Apoptosis
• Biomarkers, Tumor
• Gene Expression Profiling
• Gene Expression Regulation, Neoplastic
• Multiomics
• Neoplasms
• Prognosis

Identifiers and source

Literature Corpus work

27acf729-8938-5263-ba61-195a0b0e111f

DOI

10.21203/rs.3.rs-3737244/v1