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Article

Pan-cancer multi-omics profiling of OAS3 reveals its immunological and prognostic associations across human cancers.

PeerJ - 1 Jan 2026

Zhang Xi, Zhang Hongyan, Zhong Liang, Yang Wei, Yang Chunhui, Pan Yuqing, Liu Beizhong

Abstract excerpt

Background: The enzyme 2'-5'-oligoadenylate synthetase 3 (OAS3) plays a well-established role in antiviral immunity, but its involvement in cancer biology remains poorly understood. This study aimed to comprehensively investigate the expression patterns, mutation characteristics, prognostic significance, functional roles, and therapeutic potential of OAS3 across multiple cancer types. Methods: Utilizing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41700140
DOI: 10.7717/peerj.20805
PMCID: PMC12906706

Genes

OAS3
FLT3
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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