Article

Somatic DNA methylation heterogeneity predicts extreme transgenerational epimutation hotspots in Arabidopsis

2026-04-07

Abstract excerpt

Spontaneous epimutations are stochastic and heritable changes in cytosine methylation that arise independently of DNA sequence alterations. In plants, they occur predominantly at CG sites, accumulate across generations at high and clock-like rates, and contribute substantially to constitutive epigenetic diversity. Although these features are well established, the developmental origin of spontaneous epimutations re...

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Literature Corpus work: 2744965b-4ba1-5d6c-ad92-51945990c8ab
DOI: 10.64898/2026.04.04.716457

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