Article

AlphaBeta: Computational inference of epimutation rates and spectra from high-throughput DNA methylation data in plants

2019-12-02

Abstract excerpt

<h4>Introduction</h4> Heritable changes in cytosine methylation can arise stochastically in plant genomes independently of DNA sequence alterations. These so-called ‘spontaneous epimutations’ appear to be a byproduct of imperfect DNA methylation maintenance during mitotic or meitotic cell divisions. Accurate estimates of the rate and spectrum of these stochastic events are necessary to be able to quantify how epi...

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Literature Corpus work: a488d86f-e651-538e-87da-cebb06322b91
DOI: 10.1101/862243

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