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PD-1 upregulation enhances the immunosuppression of group 2 innate lymphoid cells by boosting IL-4 and IL-13 secretion in human non-small cell lung cancer

2020-09-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> There is increasing evidence that group 2 innate lymphoid cells (ILC2s) play an essential role in allergy and parasitic infection. However, the role of ILC2s in human lung cancer remains unclear. <bold>Methods:</bold> ILC2s from peripheral blood mononuclear cells (PBMCs) obtained from healthy donors (HDs) and non-small cell lung cancer (NSCLC) patients, and NSCL...

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Literature Corpus work
27352ec5-7030-551f-adb2-aba652f31ef1
DOI
10.21203/rs.3.rs-66230/v1
Open publication

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PD-1 upregulation enhances the immunosuppression of group 2 innate lymphoid cells by boosting IL-4 and IL-13 secretion in human non-small cell lung cancerDOI 10.21203/rs.3.rs-66230/v1
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