Article

Development of an Escape-resistant SARS CoV-2 Neutralizing Synthetic Nanobody

2022-06-07

Abstract excerpt

An emerging COVID-19 pandemic resulted in a global crisis, but also accelerated vaccine development and antibody discovery. In this work, we identified a number of nanomolar-range affinity VHH binders to SARS-CoV-2 variants of concern (VoC) receptor binding domains (RBD), by screening synthetic humanized antibody library with more than 10 11 diversity. In order to explore the most robust and fast method for affin...

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Literature Corpus work: 2719c36f-edac-5024-a94c-9b3e0b2f1f12
DOI: 10.1101/2022.06.07.495065

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