Article

Transcriptomic Analysis of Identical Twins with ALD and Different Onset Ages

2024-10-16

Abstract excerpt

<title>Abstract</title> <p>Background Adrenoleukodystrophy (ALD) is a rare X-linked neurogenetic disease caused by mutations in the <italic>ABCD1</italic> gene. Currently, the molecular mechanisms underlying the onset and severity of ALD still remain unclear. Therefore, the aim of this paper is to mine information on candidate genes associated with onset and severity of ALD by transcriptome sequencing of whole b...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3ce3a88a-4620-5e80-b171-8c3fd06350eb
DOI: 10.21203/rs.3.rs-4938524/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptomic Analysis of Identical Twins with ALD and Different Onset AgesDOI 10.21203/rs.3.rs-4938524/v1Read

Transcriptomic Analysis of Identical Twins with Different Onset Ages of AdrenoleukodystrophySemantic proximity Read

Regulatory network underlying alterations of gene expression in early death of Huntington's diseaseSemantic proximity Read

Identification of differentially expressed genes in Cushing's disease by integrated bioinformatics analysisSemantic proximity Read

Deciphering the modifiers for phenotypic variability of X-linked adrenoleukodystrophySemantic proximity Read

Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's diseaseSemantic proximity Read

Life and maladies in the grey area between the up & down regulation of GATA6: Uncharted spots of beta-pancreatic islet cells.Semantic proximity Read

Investigation of gene expression and genetic simultaneous control associated with erectile dysfunction and diabetesSemantic proximity Read

Diverse clinical manifestations of X-linked adrenoleukodystrophy in a Chinese family with identical multisite variants of ABCD1 gene.Semantic proximity Read

Identification of two novel mutations of ABCD1 gene in pedigrees with X‐linked adrenoleukodystrophySemantic proximity Read

Identification of Two Novel Mutations of ABCD1 Gene in Pedigrees With X‐linked Adrenoleukodystrophy and Review of the LiteraturesSemantic proximity Read

Exploring biomarkers and transcriptional factors in type 2 diabetes by comprehensive bioinformatics analysis on RNA-Seq and scRNA-Seq dataSemantic proximity Read

Inferring Bona Fide Differentially Expressed Genes and Their Variants Associated With Vitamin K Deficiency Using Systems Genetics ApproachSemantic proximity Read