Article

Balancing selection at a premature stop mutation in the <i>myostatin</i> gene underlies a recessive leg weakness syndrome in pigs

2018-10-12

Abstract excerpt

<h4>ABSTRACT</h4> Balancing selection provides a plausible explanation for the maintenance of deleterious alleles at moderate frequency in livestock, including lethal recessives exhibiting heterozygous advantage in carriers. In the current study, a leg weakness syndrome causing mortality of piglets in a commercial line showed monogenic recessive inheritance, and a region on chromosome 15 associated with the syndr...

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Literature Corpus work: 267887b7-4801-5267-9cd7-07411c5264b7
DOI: 10.1101/442012

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