Article

Deep-learning enables proteome-scale identification of phase-separated protein candidates from immunofluorescence images

2019-05-14

Abstract excerpt

Intrinsically disordered region (IDR) analysis has been widely used in the screening of phase-separated proteins. However, the precise sequences determining phase separation remain unclear. Furthermore, a large number of phase-separated proteins that exhibit relatively low IDR content remain uncharacterized. Phase-separated proteins appear as spherical droplet structures in immunofluorescence (IF) images, which re...

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Literature Corpus work: 2603be61-526a-563a-b4f5-08db5a4ebaaf
DOI: 10.1101/636738

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