Article

Integrating vascular and hypertrophic cartilage microtissues to fabricate scaled-up grafts for endochondral bone tissue engineering

2026-07-15

Abstract excerpt

<h4> ABSTRACT </h4> The repair of large bone defects remains a major clinical challenge, in part due to inadequate vascularization and poor integration of graft materials. Tissue engineering strategies that recapitulate the developmental process of endochondral ossification, whereby a cartilage template remodels into bone, have shown significant potential in pre-clinical models of large bone defect healing. Howe...

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Literature Corpus work: d3ab035c-b915-5422-a1f4-d4541d6be49a
DOI: 10.64898/2026.07.13.738124

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