Article

High contrast probe cleavage detection on porous silicon biosensors via quantum dot labeled DNA probes

2020-10-08

Abstract excerpt

Using porous silicon (PSi) interferometer sensors, we show the first experimental implementation of the high contrast probe cleavage detection (HCPCD) mechanism. HCPCD makes use of dramatic optical signal amplification caused by cleavage of high-contrast nanoparticle labels on probes instead of the capture of low-index biological molecules. An approximately 2 nm reflectance peak shift was detected after cleavage o...

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Literature Corpus work: 25d0e67b-9dbb-5a77-a7c7-87ea8854e43a
DOI: 10.1101/2020.10.07.330589

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