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Calreticulin-targeting trisaccharide Glc-Man-Man ligand conjugated with zinc chlorophyll derivative as a photosensitizer

2025-11-21

Abstract excerpt

<title>Abstract</title> <p> We report the design and synthesis of a novel calreticulin (CRT)-targeting trisaccharide (Glucoseα1-3Mannoseα1-2Mannose, <bold>G1M2</bold> ) ligand, <bold>G1M2-EG8-ZnChl</bold> , bearing a zinc chlorophyll derivative ( <bold>ZnChl</bold> ) as a photosensitizer. The ligand was constructed by conjugating the CRT-recognizing trisaccharide to the chlorophyll moiety via a glycine and...

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Literature Corpus work
255a6682-843a-54ea-8e08-d8680f66cf0d
DOI
10.21203/rs.3.rs-8046964/v1
Open publication

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Calreticulin-targeting trisaccharide Glc-Man-Man ligand conjugated with zinc chlorophyll derivative as a photosensitizerDOI 10.21203/rs.3.rs-8046964/v1
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