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Article

Interaction of glycyrol with calcineurin A studied by spectroscopic methods and docking.

IUBMB life - 1 Jan 2011

Peng Liqin, Qi Yao, Wu Hezhen, Wei Qun

Abstract excerpt

We have shown previously that glycyrol has an inhibitory effect on the immune response in mice by reducing calcineurin activity (Li et al., 2010, Pharm Biol 48:1177–1184). Here, we investigated the interaction of glycyrol with calcineurin A (CNA, catalytic A subunit of calcineurin) by spectroscopic methods and docking. We showed that glycyrol binds to CNA via hydrophobic interactions in a ratio of 1:1, and the...

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Identifiers

PMID: 21280172
DOI: 10.1002/iub.408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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