Article
Mannose-recognition mutant of the galactose/N-acetylgalactosamine-specific C-type lectin CEL-I engineered by site-directed mutagenesis.
Biochimica et biophysica acta - 1 Jul 2015
Moriuchi Hiromi, Unno Hideaki, Goda Shuichiro, Tateno Hiroaki, Hirabayashi Jun, Hatakeyama Tomomitsu
Abstract excerpt
BACKGROUND: CEL-I is a galactose/N-acetylgalactosamine-specific C-type lectin isolated from the sea cucumber Cucumaria echinata. Its carbohydrate-binding site contains a QPD (Gln-Pro-Asp) motif, which is generally recognized as the galactose specificity-determining motif in the C-type lectins. In...
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