Article

Sex differences in viral entry protein expression and host transcript responses to SARS-CoV-2

2020-12-31

Abstract excerpt

Epidemiological studies suggest that men exhibit a higher mortality rate to COVID-19 than women, yet the underlying biology is largely unknown. Here, we seek to delineate sex differences in the gene expression of viral entry proteins ACE2 and TMPRSS2, and host transcriptional responses to SARS-CoV-2 through large-scale analysis of genomic and clinical data. We first compiled 220,000 human gene expression profiles...

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Literature Corpus work: 9bbca080-4880-58ff-b0bb-f5590a5078df
DOI: 10.21203/rs.3.rs-100914/v2

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