Article

Resilience to dominant genetic disease in the healthy elderly

2019-10-22

Abstract excerpt

<h4>ABSTRACT</h4> Here we describe genomic screening of the healthy elderly to identify those resilient to adult-onset genetic disease, despite being at exceptionally high genetic risk. We sequenced 13,131 individuals aged 70 or older (mean age 75 years) from the ASPirin in Reducing Events in the Elderly (ASPREE) trial. Participants had no prior history of cardiovascular disease, life-threatening cancer, persisten...

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Literature Corpus work: 252b29c0-fc99-5b76-a850-0265febdc851
DOI: 10.1101/19006932

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