Article

Declining autophagy drives age-related axonal decay through microtubule alterations

2026-06-02

Abstract excerpt

The microtubule cytoskeleton plays a pivotal role in maintaining axonal integrity, and its deterioration has been closely associated with neuronal decay during ageing. Autophagy, a crucial cellular degradation process, is essential for sustaining neuronal homeostasis and its dysregulation has been implicated in various neurodegenerative diseases. Changes in autophagy are also associated with ageing. However, the m...

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Literature Corpus work: 25291978-1e6d-5e0a-b698-344e303af7ca
DOI: 10.64898/2026.05.29.728680

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