Article

AZFa Y Gene, DDX3Y, Evolved Novel Testis Transcript Variants in Primates with Proximal 3´UTR Polyadenylation for Germ Cell Specific Translation

2021-12-08

Abstract excerpt

Translational control is a major level of gene expression regulation in the male germ line. DDX3Y located in the AZFa region of the human Y chromosome encodes a conserved RNA helicase important for translational control at the G1-S phase of the cell cycle. In human, DDX3Y protein is expressed only in premeiotic male germ cells. In primates, DDX3Y evolved a second promoter producing novel testis-specific transcript...

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Literature Corpus work: 249be933-6ae5-5dd2-ab68-5cc8ea42ae9c
DOI: 10.21203/rs.3.rs-1110238/v1

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