Improved detection and classification of plasmids from circularized and fragmented assemblies

Abstract excerpt

Plasmids are mobile genetic elements important for bacterial adaptation. The study of plasmids from sequencing data is challenging because short reads produce fragmented assemblies, requiring of subsequent discrimination between chromosome and plasmid sequences. Although circularized assemblies are now possible using long-read data, there is still a need to differentiate plasmids from other circular elements. Here...

Topics

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• DNA Copy Number Variations
• Genetic Association Studies
• Genome, Bacterial
• High-Throughput Nucleotide Sequencing
• Klebsiella pneumoniae
• Microbial Sensitivity Tests
• Plasmids
• Salmonella enterica

Identifiers and source

Literature Corpus work

248ca3ec-2f5a-5211-a7d3-2b282fbbc8c9

DOI

10.1101/2022.08.04.502827