Conserved spatiotemporal expression landscape of dominant tRNA genes in human and mouse

Abstract excerpt

Transfer RNAs are integral for protein synthesis and the interpretation of the information contained in DNA. To date, a few methods, including custom microarrays and custom targeted sequencing, have been used to quantify tRNA. However, methods using available RNA-sequencing data have not yet been reported. We created a bioinformatics pipeline to quantify the highly expressed tRNAs in RNA-Seq effectively, demonstra...

Topics

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• Anticodon
• Base Pair Mismatch
• Evolution, Molecular
• Genetic Variation
• Genome, Human
• HeLa Cells
• RNA modifications and cancer
• RNA, Transfer

Identifiers and source

Literature Corpus work

2454c1b6-3760-57a7-8c42-7bc4d334a635

DOI

10.1101/2023.08.14.553175