Article

Combined omic analyses reveal novel loss-of-function <i>NLGN3</i> variants in GnRH deficiency and autism

2022-05-25

Abstract excerpt

Gonadotropin releasing hormone (GnRH) deficiency is a disorder characterized by absent or delayed puberty, with largely unknown genetic causes. The purpose of this study was to obtain and exploit gene expression profiles of GnRH neurons during development to unveil novel biological mechanisms and genetic determinants underlying GnRH deficiency (GD). Here, we combined bioinformatic analyses of primary embryonic and...

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Literature Corpus work: 240119a8-68dd-5ce6-a128-ad74d61fd076
DOI: 10.1101/2022.05.24.22275221

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Combined omic analyses reveal novel loss-of-function <i>NLGN3</i> variants in GnRH deficiency and autismDOI 10.1101/2022.05.24.22275221Read

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