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Article

Autism-linked NLGN3 is a key regulator of gonadotropin-releasing hormone deficiency

22 Feb 2023

Abstract excerpt

Gonadotropin-releasing hormone (GnRH) deficiency (GD) is a disorder characterized by absent or delayed puberty, with largely unknown genetic causes. The purpose of this study was to obtain and exploit gene expression profiles of GnRH neurons during development to unveil novel biological mechanisms and genetic determinants underlying GD. Here, we combined bioinformatic analyses of immortalized and primary...

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PMID: 36810932
DOI: 10.1242/dmm.049996

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