Article

Modelling the impact of cellular variation on flux through base excision DNA repair

2019-01-01

Abstract excerpt

Base excision repair (BER) is a pathway that repairs DNA damage inflicted by oxidative stress, certain alkylating agents, and spontaneous hydrolysis. Assays to measure the BER pathway are usually limited by being low-throughput, time consuming, and unable to measure each step of the pathway in addition to complete repair. The aim of the present work was to develop an assay format to overcome these limitations, and...

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Literature Corpus work: 23df36c1-43cd-5582-9248-0e8febbe8d6f
DOI: 10.15126/thesis.00850299

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