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Long Non-Coding RNA CRNDE is Involved in Resistance to EGFR Tyrosine Kinase Inhibitor in EGFR-Mutant Lung Cancer via eIF4A3/MUC1/EGFR Signaling

2021-01-13

Abstract excerpt

<title>Abstract</title> <p><bold>Introduction: </bold>Acquired resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) is an intractable challenge for many clinical oncologists. The mechanisms of resistance to EGFR-TKIs are complex. Long non-coding RNAs (lncRNAs) may play an important role in cancer development and metastasis. However, the biological process between lncRNAs and drug...

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Literature Corpus work
23c52f14-9e3d-5aa3-9662-b2937e499d59
DOI
10.21203/rs.3.rs-137571/v1
Open publication

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Long Non-Coding RNA CRNDE is Involved in Resistance to EGFR Tyrosine Kinase Inhibitor in EGFR-Mutant Lung Cancer via eIF4A3/MUC1/EGFR SignalingDOI 10.21203/rs.3.rs-137571/v1
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