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Article

Microarray expression profile of long non-coding RNAs in EGFR-TKIs resistance of human non-small cell lung cancer

2 Dec 2014

Abstract excerpt

The application of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) is limited by drug resistance in non-small cell lung cancer (NSCLC). Long non-coding RNAs (lncRNAs) are known to be involved in tumor development and metastasis, as well as chemotherapy resistance. To gain insight into the molecular mechanisms of EGFR-TKIs resistance, EGFR-TKIs‑sensitive and ‑resistant human lung cancer...

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PMID: 25482516
DOI: 10.3892/or.2014.3643

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