Article

The Parkinson’s drug entacapone disrupts gut microbiome homeostasis via iron sequestration

2023-11-12

Abstract excerpt

Increasing evidence shows that many human-targeted drugs alter the gut microbiome, leading to implications for host health. However, much less is known about the mechanisms by which drugs target the microbiome and how drugs affect microbial function. Here we combined quantitative microbiome profiling, long-read metagenomics, stable isotope probing and single cell chemical imaging to investigate the impact of two w...

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Literature Corpus work: 23c16b52-91ea-5337-ad6b-10dcba93dcfe
DOI: 10.1101/2023.11.12.566429

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