Back to search

Article

Coffee Extracts and Chlorogenic Acid Inhibit Proliferation of HepG2 Cells and c-Myc Expression Without Significant Modulation of Wnt/β-Catenin Signaling

2025-07-10

Abstract excerpt

Hepatocellular carcinoma (HCC) is the most common type of liver cancer. It is associated with poor clinical prognosis and a high mortality, despite the advances related to therapeutic options for HCC. Therefore, exploring alternative therapeutic options and its associated mechanisms is relevant and urgently needed. Natural products may be an important source of novel anti-cancer compounds. Coffee consumption is as...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
23ae8fa9-cbeb-525a-b06f-e558af5c8c6b
DOI
10.20944/preprints202507.0899.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Coffee Extracts and Chlorogenic Acid Inhibit Proliferation of HepG2 Cells and c-Myc Expression Without Significant Modulation of Wnt/β-Catenin SignalingDOI 10.20944/preprints202507.0899.v1
Coffee Bean and Its Chemical Constituent Caffeine and Chlorogenic Acid as Promising Chemoprevention Agents: Updated Biological Studies against Cancer CellsSemantic proximity
Caffeic Acid's Influence on the Viability and Apoptosis of a Diverse Array of Cancer Cell LinesSemantic proximity
Epigallocatechin-3-Gallate Therapeutic Potential in Cancer: Mechanism of Action and Clinical ImplicationsSemantic proximity
Antitumor Effects of Freeze‐Dried Robusta Coffee (Coffea canephora) Extracts on Breast Cancer Cell LinesSemantic proximity
Chlorogenic acid modulates hypoxia response of Hep3B cellsSemantic proximity
Identification of Synergistic Interaction Between Cannabis-Derived Compounds for Cytotoxic Activity in Colorectal Cancer Cell Lines and Colon Polyps That Induces Apoptosis-Related Cell Death and Distinct Gene ExpressionSemantic proximity
Natural Compounds in Cancer Prevention: Effects of Coffee Extracts and Their Main Polyphenolic Component, 5‐O‐Caffeoylquinic Acid, on Oncogenic Ras ProteinsSemantic proximity
Tigecycline causes loss of cell viability mediated by mitochondrial OXPHOS and RAC1 in hepatocellular carcinoma cellsSemantic proximity
Epigallocatechin Gallate Induces Hepatic Stellate Cell Senescence and Attenuates Development of Hepatocellular Carcinoma.Semantic proximity
Oleocanthal exerts antitumor effects on human liver and colon cancer cells through ROS generationSemantic proximity
Anticancer Activity of Protocatechualdehyde in Human Breast Cancer CellsSemantic proximity
siRNA-mediated beta-catenin knockdown in human hepatoma cells results in decreased growth and survival.Semantic proximity
Select a neighboring publication to make it the new centre.