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Anticancer Activity of Protocatechualdehyde in Human Breast Cancer Cells

8 Apr 2014

Abstract excerpt

Protocatechualdehyde (PCA) is a natural polyphenol compound isolated from the root of the herb S. miltiorrhiza and barley tea plants. PCA possesses antiproliferative and pro-apoptotic properties in human colorectal cancer cells. However, the cellular mechanism has not been fully understood. β-catenin and cyclin D1 are proto-oncogene that is overexpressed in many types of cancers and leads to cancer development....

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PMID: 24712725
DOI: 10.1089/jmf.2013.0159

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