Article

Hepatocyte Dedifferentiation Profiling In Alcohol-Related Liver Disease Identifies CXCR4 As A Driver Of Cell Reprogramming

2023-04-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and Aims</h4> Loss of hepatocyte identity is associated with impaired liver function in alcohol-related hepatitis (AH). In this context, hepatocyte dedifferentiation gives rise to cells with a hepatobiliary (HB) phenotype expressing biliary and hepatocytes markers and showing immature features. However, the mechanisms and the impact of hepatocyte dedifferentiation in liver diseas...

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Literature Corpus work: 2394fcfb-6acf-51a8-baa0-8c257783f97a
DOI: 10.1101/2023.04.04.535566

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