Article

Multi-compartment tumor organoids

2020-11-04

Abstract excerpt

Organoid cultures are widely used because they preserve many features of cancer cells in vivo . Here, we developed high-throughput oil-in-water droplet microtechnology to generate highly uniform, small-volume, multi-compartment organoids. Each organoid culture features a microenvironmental architecture that mimics both the basement membrane and stromal barriers. This matrix architecture, which allows accessing bo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 238e0228-235b-5833-8284-feb242c2c121
DOI: 10.1101/2020.11.03.367334

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multi-compartment tumor organoidsDOI 10.1101/2020.11.03.367334Read

Microfluidic droplet encapsulation-guided organoid growth promotes parental tumor phenotype recapitulation.Semantic proximity Read

Droplet-engineered organoids recapitulate parental tissue transcriptome with inter-organoid homogeneity and inter-tumor cell heterogeneitySemantic proximity Read

Modeling methods of different tumor organoids and their application in tumor drug resistance researchSemantic proximity Read

Patient-derived organoids in translational oncology and drug screeningSemantic proximity Read

Organoid Models for Cancer ResearchSemantic proximity Read

A patient-specific lung cancer assembloid model with heterogeneous tumor microenvironmentsSemantic proximity Read

Cancer research using organoid technologySemantic proximity Read

Drug screening model meets cancer organoid technologySemantic proximity Read

Application of cancer organoids: The forefront of personalized oncology and preclinical testingSemantic proximity Read

Tumor organoids for cancer research and personalized medicineSemantic proximity Read

A suspension technique for efficient large-scale cancer organoid culturing and perturbation screensSemantic proximity Read

Application of Ovarian Cancer Organoids in Precision Medicine: Key Challenges and Current OpportunitiesSemantic proximity Read