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Article

Uncovering endothelial to mesenchymal transition drivers in atherosclerosis via multi-omics analysis.

BMC cardiovascular disorders - 17 Feb 2025

Huang Qingyan, Gan Yuhong, Zheng Xiaoqi, Yu Zhikang, Huang Qionghui, Huang Mingfeng

Abstract excerpt

PURPOSE: This study aimed to identify novel candidates that regulate Endothelial to mesenchymal transition(EndMT) in atherosclerosis by integrating multi-omics data. METHODS: The single-cell RNA sequencing (scRNA-seq) dataset GSE159677, bulk RNA-seq dataset GSE118446 and microarray dataset GSE56309 were obtained from the Gene Expression Omnibus (GEO) database. The uniform manifold approximation and projection...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39956907
DOI: 10.1186/s12872-025-04571-5
PMCID: PMC11831781

Genes

ESM1
FN1
PTGS2
RASD1
SEMA3C
SERPINE1
TPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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