Back to search

Article

Gastric Metastasis and Transformation of Primary Lung Adenocarcinoma to Small Cell Cancer After Acquired Resistance to EGFR-TkIs: A Case Report

2021-06-11

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Transformation to small cell lung cancer (SCLC) is one of the mechanisms of resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). However, no standard treatment is available after the transformation. In addition, gastric metastasis of primary lung cancer is rarely observed, thus, little is known about its metastasis characteristi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
2371593d-f56d-5060-9c6f-62c296a9c4e3
DOI
10.21203/rs.3.rs-606938/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Gastric Metastasis and Transformation of Primary Lung Adenocarcinoma to Small Cell Cancer After Acquired Resistance to EGFR-TkIs: A Case ReportDOI 10.21203/rs.3.rs-606938/v1
Dynamic changes of acquired T790M mutation and small cell lung cancer transformation in a patient with EGFR-mutant adenocarcinoma after first- and third-generation EGFR-TKIs: a case reportSemantic proximity
Small-cell lung cancer with a rare epidermal growth factor receptor gene mutation showing "wax-and-wane" transformation.Semantic proximity
The disappearance of gastric metastasis and liver metastasis in non-small cell lung adenocarcinoma is due to osimertinib.Semantic proximity
Comprehensive molecular and clinical insights into non-small cell lung cancer transformation to small cell lung cancer with an illustrative case report.Semantic proximity
Molecular mechanisms and therapeutic strategies for small‑cell lung cancer transformation after TKI therapy in EGFR‑mutated lung adenocarcinoma (Review)Semantic proximity
Small cell lung cancer transformation: From pathogenesis to treatment.Semantic proximity
[Research Advances on Transformation to Small Cell Lung Cancer].Semantic proximity
Small cell lung cancer transformations from non-small cell lung cancer: Biological mechanism and clinical relevanceSemantic proximity
Rare transformation from lung adenocarcinoma to sarcomatoid carcinoma mediates resistance to inhibitors targeting different driver oncogenesSemantic proximity
Small cell transformation of non-small cell lung cancer under immunotherapy: Case series and literature review.Semantic proximity
Transformation to small cell lung cancer as an acquired resistance mechanism in EGFR-mutant lung adenocarcinoma: a case report of complete response to etoposide and cisplatin.Semantic proximity
Large Cell Neuroendocrine Carcinoma Transformation and EGFR-T790M Mutation as Coexisting Mechanisms of Acquired Resistance to EGFR-TKIs in Lung Cancer.Semantic proximity
Select a neighboring publication to make it the new centre.