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Article

Small cell lung cancer transformation: From pathogenesis to treatment.

Seminars in cancer biology - 1 Nov 2022

Yin Xiaomeng, Li Yueyi, Wang Hang, Jia Tingting, Wang Enli, Luo Yuling, Wei Yuhao, Qin Zeyi, Ma Xuelei

Abstract excerpt

Small cell lung cancer (SCLC) is a type of neuroendocrine tumor with high malignancy and poor prognosis. Besides the de novo SCLC, there is transformed SCLC, which has similar characteristics of pathological morphology, molecular characteristics, clinical manifestations and drug sensitivity. However, de novo SCLC and transformed SCLC have different pathogenesis and tumor microenvironment. SCLC transformation is...

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Identifiers

PMID: 35276343
DOI: 10.1016/j.semcancer.2022.03.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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