Article

Pan-cancer repository of validated natural and cryptic mRNA splicing mutations

2019-09-06

Abstract excerpt

We present a major public resource of mRNA splicing mutations validated according to multiple lines of evidence of abnormal gene expression. Likely mutations present in all tumor types reported in the Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC) were identified based on the comparative strengths of splice sites in tumor versus normal genomes, and then validated by respectively c...

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Identifiers and source

Literature Corpus work: 236bc83d-4136-505d-9fe3-93f82e1226ee
DOI: 10.12688/f1000research.17204.3

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