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Article

Role of non-coding sequence variants in cancer.

Nature reviews. Genetics - 1 Feb 2016

Khurana Ekta, Fu Yao, Chakravarty Dimple, Demichelis Francesca, Rubin Mark A, Gerstein Mark

Abstract excerpt

Patients with cancer carry somatic sequence variants in their tumour in addition to the germline variants in their inherited genome. Although variants in protein-coding regions have received the most attention, numerous studies have noted the importance of non-coding variants in cancer. Moreover, the overwhelming majority of variants, both somatic and germline, occur in non-coding portions of the genome. We...

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Identifiers

PMID: 26781813
DOI: 10.1038/nrg.2015.17

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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