Article

A dual-fluorescent recombinant for live observation of Herpes simplex-type 1 infection outcomes

2023-06-07

Abstract excerpt

Critical stages of lytic Herpes simplex type 1 (HSV-1) replication are marked by the sequential expression of immediate early (IE) to early (E), then late (L) viral genes. HSV-1 also persists in neuronal tissues via a non-replicative, transcriptionally repressed infection called latency. Understanding the regulation of lytic and latent transcriptional profiles provides focused insight into HSV-1 infection and dise...

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Literature Corpus work: fcd6b6ce-c98f-5f55-8c57-f37f33321a37
DOI: 10.1101/2023.06.07.544108

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