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Polyamine metabolism patterns characterized tumor microenvironment, prognosis, and response to immunotherapy in colorectal cancer

2022-10-18

Abstract excerpt

<h4>Background: </h4> Changes of Polyamine metabolism (PAM) have been shown to establish a suppressive tumor microenvironment (TME) and substantially influence the progression of cancer in the recent studies. However, newly emerging data were still unable to fully illuminate the specific effects of PAM in human cancers. Here, we analyzed the expression profiles and clinical relevance of PAM genes in CRC. Methods...

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Literature Corpus work
23114f99-0a9f-5c50-97ae-54c16ff9e285
DOI
10.21203/rs.3.rs-2165716/v1
Open publication

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