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Epigenetic Mechanisms Underlying Sex Differences in Neurodegenerative Diseases

19 Jan 2025

Abstract excerpt

Neurodegenerative diseases are characterized by profound differences between females and males in terms of incidence, clinical presentation, and disease progression. Furthermore, there is evidence suggesting that differences in sensitivity to medical treatments may exist between the two sexes. Although the role of sex hormones and sex chromosomes in driving differential susceptibility to these diseases is...

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PMID: 39857328
DOI: 10.3390/biology14010098

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