Article

Using Genetically Encoded Fluorescent Biosensors to Interrogate Ovarian Cancer Metabolism

2022-04-21

Abstract excerpt

<h4>Background: </h4> Epithelial ovarian cancer (OC) is the most lethal gynecological malignancy and patients present with significant metastatic burden, particularly to the adipose-rich microenvironment of the omentum. Recent evidence has highlighted the importance of metabolic adaptations in enabling this metastasis, leading to significant interest in evolving the arsenal of tools used to study OC metabolism. In...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 22ca9d19-0143-5f15-864f-0c04f39a82c6
DOI: 10.21203/rs.3.rs-1562722/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Using Genetically Encoded Fluorescent Biosensors to Interrogate Ovarian Cancer MetabolismDOI 10.21203/rs.3.rs-1562722/v1Read

Wide-field optical redox imaging with leading-edge detection for assessment of patient-derived cancer organoidsSemantic proximity Read

Wide-Field Optical Redox Imaging with Leading-Edge Detection Enables Assessment of Treatment Response and Heterogeneity in Patient-Derived Cancer Organoids.Semantic proximity Read

Targeting metabolic fluxes reverts metastatic transitions in ovarian cancerSemantic proximity Read

Optical Metabolic Imaging of Heterogeneous Drug Response in Pancreatic Cancer Patient OrganoidsSemantic proximity Read

PhenoMetaboDiff: R Package for Analysis and Visualization of Phenotype Microarray Data.Semantic proximity Read

Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib.Semantic proximity Read

Assay of the Multiple Energy-Producing Pathways of Mammalian CellsSemantic proximity Read

Adipocytes reprogram glucose metabolism in cancer cells promoting metastasisSemantic proximity Read

Quantitative Spatial Analysis of Metabolic Heterogeneity Across in vivo and in vitro Tumor ModelsSemantic proximity Read

Protocol for Seahorse 3D Mito Stress assay in patient-derived pediatric brain tumor single neurospheresSemantic proximity Read

Potent organo-osmium compound shifts metabolism in epithelial ovarian cancer cells.Semantic proximity Read

Metabolic profiling studies of tumour cell phenotypesSemantic proximity Read