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Amino acids exchange in patients with CKD as obtained via exome sequencing differ radically from those of natural variants 1000 genome and genomAD databases

2023-09-14

Abstract excerpt

<h4>Background: </h4> Nonsynonymous mutations in the coding regions of human genes are responsible for phenotypic differences between humans and for their susceptibility to genetic disease. <h4>Methods: </h4>: We performed Exome sequencing on CKD patients’ genomic DNA and put the focus in understanding the role played by the amino-acid mutation spectrum (PAM) in human chronic kidney disease CKD patients. More spe...

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Literature Corpus work: 22c3ebb9-92f4-5dd6-8ca4-be18add7d39e
DOI: 10.21203/rs.3.rs-3344794/v1

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